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Computational Prediction of Neutralization Epitopes Targeted by Human Anti-V3 HIV Monoclonal Antibodies
The extreme diversity of HIV-1 strains presents a formidable challenge for HIV-1 vaccine design. Although antibodies (Abs) can neutralize HIV-1 and potentially protect against infection, antibodies that target the immunogenic viral surface protein gp120 have widely variable and poorly predictable cr...
Autores principales: | Shmelkov, Evgeny, Krachmarov, Chavdar, Grigoryan, Arsen V., Pinter, Abraham, Statnikov, Alexander, Cardozo, Timothy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934971/ https://www.ncbi.nlm.nih.gov/pubmed/24587168 http://dx.doi.org/10.1371/journal.pone.0089987 |
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