Cargando…
Physiological implications of NTBI uptake by T lymphocytes
In iron overload disorders a significant fraction of the total iron circulates in the plasma as low molecular weight complexes not bound to transferrin, known as non-transferrin-bound iron (NTBI). By catalyzing the formation of free radicals, NTBI accumulation results in oxidative stress and cellula...
Autores principales: | Pinto, Jorge P., Arezes, João, Dias, Vera, Oliveira, Susana, Vieira, Inês, Costa, Mónica, Vos, Matthijn, Carlsson, Anna, Rikers, Yuri, Rangel, Maria, Porto, Graça |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935319/ https://www.ncbi.nlm.nih.gov/pubmed/24616700 http://dx.doi.org/10.3389/fphar.2014.00024 |
Ejemplares similares
-
Non-Transferrin-Bound Iron (NTBI) Uptake by T Lymphocytes: Evidence for the Selective Acquisition of Oligomeric Ferric Citrate Species
por: Arezes, Joao, et al.
Publicado: (2013) -
NTBI levels in C282Y homozygotes after therapeutic phlebotomy
por: Ryan, Eleanor, et al.
Publicado: (2022) -
Lymphocyte Gene Expression Signatures from Patients and Mouse Models of Hereditary Hemochromatosis Reveal a Function of HFE as a Negative Regulator of CD8(+) T-Lymphocyte Activation and Differentiation In Vivo
por: Costa, Mónica, et al.
Publicado: (2015) -
Targeting DNA Methyltranferases in Urological Tumors
por: Marques-Magalhães, Ângela, et al.
Publicado: (2018) -
A study of 82 extended HLA haplotypes in HFE-C282Y homozygous hemochromatosis subjects: relationship to the genetic control of CD8+ T-lymphocyte numbers and severity of iron overload
por: Cruz, Eugénia, et al.
Publicado: (2006)