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Novel serological neo-epitope markers of extracellular matrix proteins for the detection of portal hypertension

BackgroundThe hepatic venous pressure gradient (HVPG) is an invasive, but important diagnostic and prognostic marker in cirrhosis with portal hypertension (PHT). During cirrhosis, remodelling of fibrotic tissue by matrix metalloproteinases (MMPs) is a permanent process generating small fragments of...

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Detalles Bibliográficos
Autores principales: Leeming, D J, Karsdal, M A, Byrjalsen, I, Bendtsen, F, Trebicka, J, Nielsen, M J, Christiansen, C, Møller, S, Krag, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935409/
https://www.ncbi.nlm.nih.gov/pubmed/24099470
http://dx.doi.org/10.1111/apt.12484

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