Cargando…
Extracorporeal Membrane Oxygenation in Diffuse Alveolar Hemorrhage Secondary to Systemic Lupus Erythematosus
Diffuse alveolar hemorrhage (DAH) is a rare and potentially deadly complication of systemic lupus erythematosus (SLE). We report two adult cases where extracorporeal membrane oxygenation (ECMO) was used as rescue therapy for severe respiratory failure in this setting. We discuss the risk related to...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elmer Press
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935524/ https://www.ncbi.nlm.nih.gov/pubmed/24578757 http://dx.doi.org/10.14740/jocmr1685w |
_version_ | 1782305199093710848 |
---|---|
author | Claudio, Christine Pacheco Charbonney, Emmanuel Durand, Madeleine Kolan, Christophe Laskine, Mikhael |
author_facet | Claudio, Christine Pacheco Charbonney, Emmanuel Durand, Madeleine Kolan, Christophe Laskine, Mikhael |
author_sort | Claudio, Christine Pacheco |
collection | PubMed |
description | Diffuse alveolar hemorrhage (DAH) is a rare and potentially deadly complication of systemic lupus erythematosus (SLE). We report two adult cases where extracorporeal membrane oxygenation (ECMO) was used as rescue therapy for severe respiratory failure in this setting. We discuss the risk related to coagulation disturbance and the need for the circuit anticoagulation in this particular setting. We also briefly discuss the clinical problem of lack of knowledge on the bioavailability of the immunosuppressive treatment with the use of ECMO. We think that ECMO should be used as rescue therapy in patients with DAH caused by SLE, but strategies for anticoagulation require further precision. |
format | Online Article Text |
id | pubmed-3935524 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Elmer Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-39355242014-02-26 Extracorporeal Membrane Oxygenation in Diffuse Alveolar Hemorrhage Secondary to Systemic Lupus Erythematosus Claudio, Christine Pacheco Charbonney, Emmanuel Durand, Madeleine Kolan, Christophe Laskine, Mikhael J Clin Med Res Case Report Diffuse alveolar hemorrhage (DAH) is a rare and potentially deadly complication of systemic lupus erythematosus (SLE). We report two adult cases where extracorporeal membrane oxygenation (ECMO) was used as rescue therapy for severe respiratory failure in this setting. We discuss the risk related to coagulation disturbance and the need for the circuit anticoagulation in this particular setting. We also briefly discuss the clinical problem of lack of knowledge on the bioavailability of the immunosuppressive treatment with the use of ECMO. We think that ECMO should be used as rescue therapy in patients with DAH caused by SLE, but strategies for anticoagulation require further precision. Elmer Press 2014-04 2014-02-06 /pmc/articles/PMC3935524/ /pubmed/24578757 http://dx.doi.org/10.14740/jocmr1685w Text en Copyright 2014, Claudio et al. http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Claudio, Christine Pacheco Charbonney, Emmanuel Durand, Madeleine Kolan, Christophe Laskine, Mikhael Extracorporeal Membrane Oxygenation in Diffuse Alveolar Hemorrhage Secondary to Systemic Lupus Erythematosus |
title | Extracorporeal Membrane Oxygenation in Diffuse Alveolar Hemorrhage Secondary to Systemic Lupus Erythematosus |
title_full | Extracorporeal Membrane Oxygenation in Diffuse Alveolar Hemorrhage Secondary to Systemic Lupus Erythematosus |
title_fullStr | Extracorporeal Membrane Oxygenation in Diffuse Alveolar Hemorrhage Secondary to Systemic Lupus Erythematosus |
title_full_unstemmed | Extracorporeal Membrane Oxygenation in Diffuse Alveolar Hemorrhage Secondary to Systemic Lupus Erythematosus |
title_short | Extracorporeal Membrane Oxygenation in Diffuse Alveolar Hemorrhage Secondary to Systemic Lupus Erythematosus |
title_sort | extracorporeal membrane oxygenation in diffuse alveolar hemorrhage secondary to systemic lupus erythematosus |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935524/ https://www.ncbi.nlm.nih.gov/pubmed/24578757 http://dx.doi.org/10.14740/jocmr1685w |
work_keys_str_mv | AT claudiochristinepacheco extracorporealmembraneoxygenationindiffusealveolarhemorrhagesecondarytosystemiclupuserythematosus AT charbonneyemmanuel extracorporealmembraneoxygenationindiffusealveolarhemorrhagesecondarytosystemiclupuserythematosus AT durandmadeleine extracorporealmembraneoxygenationindiffusealveolarhemorrhagesecondarytosystemiclupuserythematosus AT kolanchristophe extracorporealmembraneoxygenationindiffusealveolarhemorrhagesecondarytosystemiclupuserythematosus AT laskinemikhael extracorporealmembraneoxygenationindiffusealveolarhemorrhagesecondarytosystemiclupuserythematosus |