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Inhibition of GM3 Synthase Attenuates Neuropathology of Niemann-Pick Disease Type C by Affecting Sphingolipid Metabolism

In several lysosomal storage disorders, including Niemann-Pick disease Type C (NP-C), sphingolipids, including glycosphingolipids, particularly gangliosides, are the predominant storage materials in the brain, raising the possibility that accumulation of these lipids may be involved in the NP-C neur...

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Detalles Bibliográficos
Autores principales:	Lee, Hyun, Lee, Jong Kil, Bae, Yong Chul, Yang, Song Hyun, Okino, Nozomu, Schuchman, Edward H., Yamashita, Tadashi, Bae, Jae-sung, Jin, Hee Kyung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korea Society for Molecular and Cellular Biology 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935629/ https://www.ncbi.nlm.nih.gov/pubmed/24599001 http://dx.doi.org/10.14348/molcells.2014.2347

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