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Unsaturated Glycerophospholipids Mediate Heme Crystallization: Biological Implications for Hemozoin Formation in the Kissing Bug Rhodnius prolixus

Hemozoin (Hz) is a heme crystal produced by some blood-feeding organisms, as an efficient way to detoxify heme derived from hemoglobin digestion. In the triatomine insect Rhodnius prolixus, Hz is essentially produced by midgut extracellular phospholipid membranes known as perimicrovillar membranes (...

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Detalles Bibliográficos
Autores principales: Stiebler, Renata, Majerowicz, David, Knudsen, Jens, Gondim, Katia C., Wright, David W., Egan, Timothy J., Oliveira, Marcus F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935856/
https://www.ncbi.nlm.nih.gov/pubmed/24586467
http://dx.doi.org/10.1371/journal.pone.0088976