Premature CD4(+) T Cell Aging and Its Contribution to Lymphopenia-Induced Proliferation of Memory Cells in Autoimmune-Prone Non-Obese Diabetic Mice

Lymphopenia-induced proliferation (LIP), a mechanism to maintain a constant number of T cells in circulation, occurs in both normal aging and autoimmune disease. The incidence of most autoimmune diseases increases with age, and premature CD4(+) T cell aging has been reported in several autoimmune di...

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Detalles Bibliográficos
Autores principales: Sheu, Ting-Ting, Chiang, Bor-Luen, Yen, Jui-Hung, Lin, Wen-Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935863/
https://www.ncbi.nlm.nih.gov/pubmed/24586733
http://dx.doi.org/10.1371/journal.pone.0089379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935863/
https://www.ncbi.nlm.nih.gov/pubmed/24586733
http://dx.doi.org/10.1371/journal.pone.0089379

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