The Catalytic Subunit of the System L1 Amino Acid Transporter (Slc7a5) Facilitates Nutrient Signalling in Mouse Skeletal Muscle

The System L1-type amino acid transporter mediates transport of large neutral amino acids (LNAA) in many mammalian cell-types. LNAA such as leucine are required for full activation of the mTOR-S6K signalling pathway promoting protein synthesis and cell growth. The SLC7A5 (LAT1) catalytic subunit of...

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Detalles Bibliográficos
Autores principales: Poncet, Nadège, Mitchell, Fiona E., Ibrahim, Adel F. M., McGuire, Victoria A., English, Grant, Arthur, J. Simon C, Shi, Yun-Bo, Taylor, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935884/
https://www.ncbi.nlm.nih.gov/pubmed/24586861
http://dx.doi.org/10.1371/journal.pone.0089547

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935884/
https://www.ncbi.nlm.nih.gov/pubmed/24586861
http://dx.doi.org/10.1371/journal.pone.0089547

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