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Early Effects of Neutering on Energy Expenditure in Adult Male Cats

The initial cause of post-neutering weight gain in male cats is not entirely known. There is evidence that energy intake (EI) increases rapidly post-neutering, but it is not clear if neutering also decreases energy expenditure (EE) prior to weight gain. Thus, the purpose of this study was to determi...

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Autores principales: Wei, Alfreda, Fascetti, Andrea J., Kim, Kyoungmi, Lee, Ada, Graham, James L., Havel, Peter J., Ramsey, Jon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935885/
https://www.ncbi.nlm.nih.gov/pubmed/24586869
http://dx.doi.org/10.1371/journal.pone.0089557
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author Wei, Alfreda
Fascetti, Andrea J.
Kim, Kyoungmi
Lee, Ada
Graham, James L.
Havel, Peter J.
Ramsey, Jon J.
author_facet Wei, Alfreda
Fascetti, Andrea J.
Kim, Kyoungmi
Lee, Ada
Graham, James L.
Havel, Peter J.
Ramsey, Jon J.
author_sort Wei, Alfreda
collection PubMed
description The initial cause of post-neutering weight gain in male cats is not entirely known. There is evidence that energy intake (EI) increases rapidly post-neutering, but it is not clear if neutering also decreases energy expenditure (EE) prior to weight gain. Thus, the purpose of this study was to determine if a decrease in EE contributes to the initial shift toward positive energy balance in neutered male cats. To determine the influence of neutering on EE independent of changes in EI and body weight (BW), male cats were fed at their pre-neutering maintenance EI and EE was measured at 4 days pre-neutering, 3–4 days post-neutering, and 9 days post- neutering. Ad libitum food access was then provided for 6 months. Body composition was measured and blood samples collected for serum chemistry at pre-neutering and 7 days, 13 days and 6 months post-neutering. Total energy expenditure (TEE) adjusted for lean body mass (LBM) did not change in cats from pre-neutering to 9 days post-neutering. However, TEE adjusted for BW and resting energy expenditure adjusted for either LBM or BW showed a small, but significant (P<0.05) increase from pre-neutering to 9 days post-neutering. When allowed free choice food access, cats showed significant increases of food intake (FI) and BW. Circulating concentrations of ghrelin increased, while adiponectin levels decreased following neutering. The results of this study indicate that initial post-neutering weight gain in male cats results from increased FI and not decreased EE. Long-term control of FI should be initiated after neutering to prevent hyperphagia and weight gain in male cats.
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spelling pubmed-39358852014-03-04 Early Effects of Neutering on Energy Expenditure in Adult Male Cats Wei, Alfreda Fascetti, Andrea J. Kim, Kyoungmi Lee, Ada Graham, James L. Havel, Peter J. Ramsey, Jon J. PLoS One Research Article The initial cause of post-neutering weight gain in male cats is not entirely known. There is evidence that energy intake (EI) increases rapidly post-neutering, but it is not clear if neutering also decreases energy expenditure (EE) prior to weight gain. Thus, the purpose of this study was to determine if a decrease in EE contributes to the initial shift toward positive energy balance in neutered male cats. To determine the influence of neutering on EE independent of changes in EI and body weight (BW), male cats were fed at their pre-neutering maintenance EI and EE was measured at 4 days pre-neutering, 3–4 days post-neutering, and 9 days post- neutering. Ad libitum food access was then provided for 6 months. Body composition was measured and blood samples collected for serum chemistry at pre-neutering and 7 days, 13 days and 6 months post-neutering. Total energy expenditure (TEE) adjusted for lean body mass (LBM) did not change in cats from pre-neutering to 9 days post-neutering. However, TEE adjusted for BW and resting energy expenditure adjusted for either LBM or BW showed a small, but significant (P<0.05) increase from pre-neutering to 9 days post-neutering. When allowed free choice food access, cats showed significant increases of food intake (FI) and BW. Circulating concentrations of ghrelin increased, while adiponectin levels decreased following neutering. The results of this study indicate that initial post-neutering weight gain in male cats results from increased FI and not decreased EE. Long-term control of FI should be initiated after neutering to prevent hyperphagia and weight gain in male cats. Public Library of Science 2014-02-26 /pmc/articles/PMC3935885/ /pubmed/24586869 http://dx.doi.org/10.1371/journal.pone.0089557 Text en © 2014 Wei et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Wei, Alfreda
Fascetti, Andrea J.
Kim, Kyoungmi
Lee, Ada
Graham, James L.
Havel, Peter J.
Ramsey, Jon J.
Early Effects of Neutering on Energy Expenditure in Adult Male Cats
title Early Effects of Neutering on Energy Expenditure in Adult Male Cats
title_full Early Effects of Neutering on Energy Expenditure in Adult Male Cats
title_fullStr Early Effects of Neutering on Energy Expenditure in Adult Male Cats
title_full_unstemmed Early Effects of Neutering on Energy Expenditure in Adult Male Cats
title_short Early Effects of Neutering on Energy Expenditure in Adult Male Cats
title_sort early effects of neutering on energy expenditure in adult male cats
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935885/
https://www.ncbi.nlm.nih.gov/pubmed/24586869
http://dx.doi.org/10.1371/journal.pone.0089557
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