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Use of Synthetic Isoprenoids to Target Protein Prenylation and Rho GTPases in Breast Cancer Invasion

Dysregulation of Ras and Rho family small GTPases drives the invasion and metastasis of multiple cancers. For their biological functions, these GTPases require proper subcellular localization to cellular membranes, which is regulated by a series of post-translational modifications that result in eit...

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Detalles Bibliográficos
Autores principales:	Chen, Min, Knifley, Teresa, Subramanian, Thangaiah, Spielmann, H. Peter, O’Connor, Kathleen L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935959/ https://www.ncbi.nlm.nih.gov/pubmed/24587105 http://dx.doi.org/10.1371/journal.pone.0089892

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