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Post-Translational Modifications Modulate Ligand Recognition by the Third PDZ Domain of the MAGUK Protein PSD-95

The relative promiscuity of hub proteins such as postsynaptic density protein-95 (PSD-95) can be achieved by alternative splicing, allosteric regulation, and post-translational modifications, the latter of which is the most efficient method of accelerating cellular responses to environmental changes...

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Detalles Bibliográficos
Autores principales: Murciano-Calles, Javier, Corbi-Verge, Carles, Candel, Adela M., Luque, Irene, Martinez, Jose C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935999/
https://www.ncbi.nlm.nih.gov/pubmed/24587199
http://dx.doi.org/10.1371/journal.pone.0090030