Cargando…

Mercury induced the Accumulation of Amyloid Beta (Aβ) in PC12 Cells: The Role of Production and Degradation of Aβ

Extracellular accumulation of amyloid beta protein (Aβ) plays a central role in Alzheimer’s disease (AD). Some metals, such as copper, lead, and aluminum can affect the Aβ accumulation in the brain. However, the effect of mercury on Aβ accumulation in the brain is not clear. Thus, this study was pro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Song, Ji-Won, Choi, Byung-Sun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Society of Toxicology 2013
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936175/ https://www.ncbi.nlm.nih.gov/pubmed/24578793 http://dx.doi.org/10.5487/TR.2013.29.4.235

Ejemplares similares

Experimental study on the neurotoxic effect of β-amyloid on the cytoskeleton of PC12 cells
por: Wang, Lai, et al.
Publicado: (2018)

Regucalcin confers resistance to amyloid‐β toxicity in neuronally differentiated PC12 cells
por: Murata, Tomiyasu, et al.
Publicado: (2018)

Vincamine Alleviates Amyloid-β 25–35 Peptides-induced Cytotoxicity in PC12 Cells
por: Han, Jianfeng, et al.
Publicado: (2017)

β-Amyloid Degradation and Alzheimer's Disease
por: Wang, Deng-Shun, et al.
Publicado: (2006)

Intracellular accumulation of aggregated pyroglutamate amyloid beta: convergence of aging and Aβ pathology at the lysosome
por: De Kimpe, Line, et al.
Publicado: (2012)

Neuroprotective effect of hydroxy-α-sanshool against β-amyloid-induced damage in differentiated PC12 cells
por: Shan, Shufang, et al.
Publicado: (2023)

The Components of Flemingia macrophylla Attenuate Amyloid β-Protein Accumulation by Regulating Amyloid β-Protein Metabolic Pathway
por: Lin, Yun-Lian, et al.
Publicado: (2012)

The Role of Heat Shock Protein 70 in the Protective Effect of YC-1 on β-Amyloid-Induced Toxicity in Differentiated PC12 Cells
por: Tsai, Yung-Chieh, et al.
Publicado: (2013)

Role of Notch-1 signaling pathway in PC12 cell apoptosis induced by amyloid beta-peptide (25–35)
por: Liang, Huimin, et al.
Publicado: (2014)

Changes in the language system as amyloid-β accumulates
por: Reinartz, Mariska, et al.
Publicado: (2021)

β-Asarone Ameliorates β-Amyloid–Induced Neurotoxicity in PC12 Cells by Activating P13K/Akt/Nrf2 Signaling Pathway
por: Meng, Miaomiao, et al.
Publicado: (2021)

Resveratrol inhibits β-amyloid-induced neuronal apoptosis via regulation of p53 acetylation in PC12 cells
por: AI, ZHIBING, et al.
Publicado: (2015)

Ferulago angulata Methanolic Extract Protects PC12 Cells Against Beta-amyloid-induced Toxicity
por: Hashemi, Leila, et al.
Publicado: (2023)

Neuroprotective Effects of Biochanin A against β-Amyloid-Induced Neurotoxicity in PC12 Cells via a Mitochondrial-Dependent Apoptosis Pathway
por: Tan, Ji Wei, et al.
Publicado: (2016)

Rates of β-amyloid accumulation are independent of hippocampal neurodegeneration
por: Jack, Clifford R., et al.
Publicado: (2014)

Accumulation of amyloid beta in human glioblastomas
por: Zayas‐Santiago, A., et al.
Publicado: (2020)

Shikonin Protects PC12 Cells Against β-amyloid Peptide-Induced Cell Injury Through Antioxidant and Antiapoptotic Activities
por: Tong, Yuna, et al.
Publicado: (2018)

Protective Effects of the Key Compounds Isolated from Corni fructus against β-Amyloid-Induced Neurotoxicity in PC12 Cells
por: Hong, Seung-Young, et al.
Publicado: (2012)

Design and Synthesis of New Benzo[d]oxazole-Based Derivatives and Their Neuroprotective Effects on β-Amyloid-Induced PC12 Cells
por: Liu, Zheng, et al.
Publicado: (2020)

Impact of NMDA receptor activation on DNA damage in PC12 neuron-like cell cultures in the presence of β-amyloid peptides
por: Wiatrak, Benita, et al.
Publicado: (2022)

Overexpression of estrogen receptor beta alleviates the toxic effects of beta-amyloid protein on PC12 cells via non-hormonal ligands☆
por: Wang, Hui, et al.
Publicado: (2012)

Ginsenosides attenuate bioenergetics and morphology of mitochondria in cultured PC12 cells under the insult of amyloid beta-peptide
por: Kwan, Kenneth Kin Leung, et al.
Publicado: (2021)

Memory Impairment in Estrogen Receptor α Knockout Mice Through Accumulation of Amyloid-β Peptides
por: Hwang, Chul Ju, et al.
Publicado: (2014)

Accumulation of amyloid beta (Aβ) and amyloid precursor protein (APP) in tumors formed by a mouse xenograft model of inflammatory breast cancer
por: Zayas‐Santiago, Astrid, et al.
Publicado: (2021)

Amyloid precursor protein modulates β-catenin degradation
por: Chen, Yuzhi, et al.
Publicado: (2007)

In vitro degradation of β-amyloid fibrils by microbial keratinase
por: Ningthoujam, Debananda S., et al.
Publicado: (2019)

Microfluidic Chemotaxis Platform for Differentiating the Roles of Soluble and Bound Amyloid-β on Microglial Accumulation
por: Cho, Hansang, et al.
Publicado: (2013)

Hypertension drives parenchymal β-amyloid accumulation in the brain parenchyma
por: Bueche, Celine Z, et al.
Publicado: (2014)

Salidroside protects PC-12 cells against amyloid β-induced apoptosis by activation of the ERK1/2 and AKT signaling pathways
por: Liao, Zheng-Luan, et al.
Publicado: (2019)

Artemisinin protects PC12 cells against β-amyloid-induced apoptosis through activation of the ERK1/2 signaling pathway
por: Zeng, Zhiwen, et al.
Publicado: (2017)

Amyloidosis in Alzheimer's Disease: The Toxicity of Amyloid Beta (Aβ), Mechanisms of Its Accumulation and Implications of Medicinal Plants for Therapy
por: Prasansuklab, Anchalee, et al.
Publicado: (2013)

The Aqueous Extract of Rhizome of Gastrodia elata Protected Drosophila and PC12 Cells against Beta-Amyloid-Induced Neurotoxicity
por: Ng, Chun-Fai, et al.
Publicado: (2013)

Triptolide Inhibited Cytotoxicity of Differentiated PC12 Cells Induced by Amyloid-Beta(25–35) via the Autophagy Pathway
por: Xu, Pengjuan, et al.
Publicado: (2015)

Icariin Prevents Amyloid Beta-Induced Apoptosis via the PI3K/Akt Pathway in PC-12 Cells
por: Zhang, Dongdong, et al.
Publicado: (2015)

Protective effects of components of the Chinese herb grassleaf sweetflag rhizome on PC12 cells incubated with amyloid-beta42
por: Liang, Zi-hao, et al.
Publicado: (2015)

Mitogen-activated protein kinase phosphatase 1 protects PC12 cells from amyloid beta-induced neurotoxicity
por: Gu, Yue, et al.
Publicado: (2018)

Role of microglial amylin receptors in mediating beta amyloid (Aβ)-induced inflammation
por: Fu, Wen, et al.
Publicado: (2017)

Cerebrospinal fluid ratios with Aβ(42) predict preclinical brain β-amyloid accumulation
por: Racine, Annie M., et al.
Publicado: (2015)

β-Amyloid accumulation in the human brain after one night of sleep deprivation
por: Shokri-Kojori, Ehsan, et al.
Publicado: (2018)

Vitamin D and Its Analogues Decrease Amyloid-β (Aβ) Formation and Increase Aβ-Degradation
por: Grimm, Marcus O. W., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_dp60n3sj8ldlnsrmvhiktcp6o5