Cargando…

Cryptosporidium parvum IId family: clonal population and dispersal from Western Asia to other geographical regions

In this study, 111 Cryptosporidium parvum IId isolates from several species of animals in China, Sweden, and Egypt were subtyped by multilocus sequence typing (MLST). One to eleven subtypes were detected at each of the 12 microsatellite, minisatellite, and single nucleotide polymorphism (SNP) loci,...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Rongjun, Zhang, Longxian, Axén, Charlotte, Bjorkman, Camilla, Jian, Fuchun, Amer, Said, Liu, Aiqin, Feng, Yaoyu, Li, Guoquan, Lv, Chaochao, Zhao, Zifang, Qi, Meng, Dong, Haiju, Wang, Helei, Sun, Yanru, Ning, Changshen, Xiao, Lihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936226/
https://www.ncbi.nlm.nih.gov/pubmed/24572610
http://dx.doi.org/10.1038/srep04208
_version_ 1782305290638589952
author Wang, Rongjun
Zhang, Longxian
Axén, Charlotte
Bjorkman, Camilla
Jian, Fuchun
Amer, Said
Liu, Aiqin
Feng, Yaoyu
Li, Guoquan
Lv, Chaochao
Zhao, Zifang
Qi, Meng
Dong, Haiju
Wang, Helei
Sun, Yanru
Ning, Changshen
Xiao, Lihua
author_facet Wang, Rongjun
Zhang, Longxian
Axén, Charlotte
Bjorkman, Camilla
Jian, Fuchun
Amer, Said
Liu, Aiqin
Feng, Yaoyu
Li, Guoquan
Lv, Chaochao
Zhao, Zifang
Qi, Meng
Dong, Haiju
Wang, Helei
Sun, Yanru
Ning, Changshen
Xiao, Lihua
author_sort Wang, Rongjun
collection PubMed
description In this study, 111 Cryptosporidium parvum IId isolates from several species of animals in China, Sweden, and Egypt were subtyped by multilocus sequence typing (MLST). One to eleven subtypes were detected at each of the 12 microsatellite, minisatellite, and single nucleotide polymorphism (SNP) loci, forming 25 MLST subtypes. Host-adaptation and significant geographical segregation were both observed in the MLST subtypes. A clonal population structure was seen in C. parvum IId isolates from China and Sweden. Three ancestral lineages and the same RPGR sequence were shared by these isolates examined. Therefore, the present genetic observations including the higher nucleotide diversity of C. parvum IId GP60 sequences in Western Asia, as well as the unique distribution of IId subtypes (almost exclusively found in Asia, Europe, and Egypt) and in combination with the domestication history of cattle, sheep, and goats, indicated that C. parvum IId subtypes were probably dispersed from Western Asia to other geographical regions. More population genetic structure studies involving various C. parvum subtype families using high-resolution tools are needed to better elucidate the origin and dissemination of C. parvum in the world.
format Online
Article
Text
id pubmed-3936226
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher Nature Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-39362262014-03-04 Cryptosporidium parvum IId family: clonal population and dispersal from Western Asia to other geographical regions Wang, Rongjun Zhang, Longxian Axén, Charlotte Bjorkman, Camilla Jian, Fuchun Amer, Said Liu, Aiqin Feng, Yaoyu Li, Guoquan Lv, Chaochao Zhao, Zifang Qi, Meng Dong, Haiju Wang, Helei Sun, Yanru Ning, Changshen Xiao, Lihua Sci Rep Article In this study, 111 Cryptosporidium parvum IId isolates from several species of animals in China, Sweden, and Egypt were subtyped by multilocus sequence typing (MLST). One to eleven subtypes were detected at each of the 12 microsatellite, minisatellite, and single nucleotide polymorphism (SNP) loci, forming 25 MLST subtypes. Host-adaptation and significant geographical segregation were both observed in the MLST subtypes. A clonal population structure was seen in C. parvum IId isolates from China and Sweden. Three ancestral lineages and the same RPGR sequence were shared by these isolates examined. Therefore, the present genetic observations including the higher nucleotide diversity of C. parvum IId GP60 sequences in Western Asia, as well as the unique distribution of IId subtypes (almost exclusively found in Asia, Europe, and Egypt) and in combination with the domestication history of cattle, sheep, and goats, indicated that C. parvum IId subtypes were probably dispersed from Western Asia to other geographical regions. More population genetic structure studies involving various C. parvum subtype families using high-resolution tools are needed to better elucidate the origin and dissemination of C. parvum in the world. Nature Publishing Group 2014-02-27 /pmc/articles/PMC3936226/ /pubmed/24572610 http://dx.doi.org/10.1038/srep04208 Text en Copyright © 2014, Macmillan Publishers Limited. All rights reserved http://creativecommons.org/licenses/by-nc-nd/3.0/ This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/
spellingShingle Article
Wang, Rongjun
Zhang, Longxian
Axén, Charlotte
Bjorkman, Camilla
Jian, Fuchun
Amer, Said
Liu, Aiqin
Feng, Yaoyu
Li, Guoquan
Lv, Chaochao
Zhao, Zifang
Qi, Meng
Dong, Haiju
Wang, Helei
Sun, Yanru
Ning, Changshen
Xiao, Lihua
Cryptosporidium parvum IId family: clonal population and dispersal from Western Asia to other geographical regions
title Cryptosporidium parvum IId family: clonal population and dispersal from Western Asia to other geographical regions
title_full Cryptosporidium parvum IId family: clonal population and dispersal from Western Asia to other geographical regions
title_fullStr Cryptosporidium parvum IId family: clonal population and dispersal from Western Asia to other geographical regions
title_full_unstemmed Cryptosporidium parvum IId family: clonal population and dispersal from Western Asia to other geographical regions
title_short Cryptosporidium parvum IId family: clonal population and dispersal from Western Asia to other geographical regions
title_sort cryptosporidium parvum iid family: clonal population and dispersal from western asia to other geographical regions
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936226/
https://www.ncbi.nlm.nih.gov/pubmed/24572610
http://dx.doi.org/10.1038/srep04208
work_keys_str_mv AT wangrongjun cryptosporidiumparvumiidfamilyclonalpopulationanddispersalfromwesternasiatoothergeographicalregions
AT zhanglongxian cryptosporidiumparvumiidfamilyclonalpopulationanddispersalfromwesternasiatoothergeographicalregions
AT axencharlotte cryptosporidiumparvumiidfamilyclonalpopulationanddispersalfromwesternasiatoothergeographicalregions
AT bjorkmancamilla cryptosporidiumparvumiidfamilyclonalpopulationanddispersalfromwesternasiatoothergeographicalregions
AT jianfuchun cryptosporidiumparvumiidfamilyclonalpopulationanddispersalfromwesternasiatoothergeographicalregions
AT amersaid cryptosporidiumparvumiidfamilyclonalpopulationanddispersalfromwesternasiatoothergeographicalregions
AT liuaiqin cryptosporidiumparvumiidfamilyclonalpopulationanddispersalfromwesternasiatoothergeographicalregions
AT fengyaoyu cryptosporidiumparvumiidfamilyclonalpopulationanddispersalfromwesternasiatoothergeographicalregions
AT liguoquan cryptosporidiumparvumiidfamilyclonalpopulationanddispersalfromwesternasiatoothergeographicalregions
AT lvchaochao cryptosporidiumparvumiidfamilyclonalpopulationanddispersalfromwesternasiatoothergeographicalregions
AT zhaozifang cryptosporidiumparvumiidfamilyclonalpopulationanddispersalfromwesternasiatoothergeographicalregions
AT qimeng cryptosporidiumparvumiidfamilyclonalpopulationanddispersalfromwesternasiatoothergeographicalregions
AT donghaiju cryptosporidiumparvumiidfamilyclonalpopulationanddispersalfromwesternasiatoothergeographicalregions
AT wanghelei cryptosporidiumparvumiidfamilyclonalpopulationanddispersalfromwesternasiatoothergeographicalregions
AT sunyanru cryptosporidiumparvumiidfamilyclonalpopulationanddispersalfromwesternasiatoothergeographicalregions
AT ningchangshen cryptosporidiumparvumiidfamilyclonalpopulationanddispersalfromwesternasiatoothergeographicalregions
AT xiaolihua cryptosporidiumparvumiidfamilyclonalpopulationanddispersalfromwesternasiatoothergeographicalregions