Cargando…

mRNA 3′end processing: A tale of the tail reaches the clinic

Recent advances reveal mRNA 3′end processing as a highly regulated process that fine-tunes posttranscriptional gene expression. This process can affect the site and/or the efficiency of 3′end processing, controlling the quality and the quantity of substrate mRNAs. The regulation of 3′end processing...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hollerer, Ina, Grund, Kerstin, Hentze, Matthias W, Kulozik, Andreas E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell 2014
Materias:	Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936486/ https://www.ncbi.nlm.nih.gov/pubmed/24408965 http://dx.doi.org/10.1002/emmm.201303300

Ejemplares similares

The best of 25 years: mRNA 3′end processing
por: Hollerer, Ina, et al.
Publicado: (2015)

The differential expression of alternatively polyadenylated transcripts is a common stress-induced response mechanism that modulates mammalian mRNA expression in a quantitative and qualitative fashion
por: Hollerer, Ina, et al.
Publicado: (2016)

Integration of splicing, transport and translation to achieve mRNA quality control by the nonsense-mediated decay pathway
por: Schell, Thomas, et al.
Publicado: (2002)

Exon Junction Complexes Show a Distributional Bias toward Alternatively Spliced mRNAs and against mRNAs Coding for Ribosomal Proteins
por: Hauer, Christian, et al.
Publicado: (2016)

Nonsense-mediated mRNA decay: from vacuum cleaner to Swiss army knife
por: Neu-Yilik, Gabriele, et al.
Publicado: (2004)

The Hierarchy of Exon-Junction Complex Assembly by the Spliceosome Explains Key Features of Mammalian Nonsense-Mediated mRNA Decay
por: Gehring, Niels H., et al.
Publicado: (2009)

The uORF-containing thrombopoietin mRNA escapes nonsense-mediated decay (NMD)
por: Stockklausner, Clemens, et al.
Publicado: (2006)

Improved binding site assignment by high-resolution mapping of RNA–protein interactions using iCLIP
por: Hauer, Christian, et al.
Publicado: (2015)

Tales of Tails
por: Essex, Christopher, et al.
Publicado: (2023)

Tales of tails in transporters
por: Mikros, Emmanuel, et al.
Publicado: (2019)

Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA
por: Powers, Kyle T, et al.
Publicado: (2021)

Mechanistic insights into mRNA 3′-end processing
por: Kumar, Ananthanarayanan, et al.
Publicado: (2019)

A tale of (disordered) tail
por: Roychowdhury, Sumangal, et al.
Publicado: (2023)

Architecture of eukaryotic mRNA 3′-end processing machinery
por: Casañal, Ana, et al.
Publicado: (2017)

Crosstalk Between mRNA 3'-End Processing and Epigenetics
por: Soles, Lindsey V., et al.
Publicado: (2021)

“A tale of tail”: A case of lizard tail abuse
por: Das, Soumitra, et al.
Publicado: (2020)

A Tale of the Tail : A Comprehensive Understanding of the “Human Tail”
por: Tojima, Sayaka
Publicado: (2021)

Designing disorder: Tales of the unexpected tails
por: Minde, David P, et al.
Publicado: (2013)

Pathologies at the nexus of blood coagulation and inflammation: thrombin in hemostasis, cancer, and beyond
por: Danckwardt, Sven, et al.
Publicado: (2013)

A Tale of 2 mRNA Vaccines: The Spring of Hope, The Winter of Despair
por: Witberg, Guy, et al.
Publicado: (2022)

mRNA 3′ End Processing Factors: A Phylogenetic Comparison
por: Darmon, Sarah K., et al.
Publicado: (2012)

Human pre-mRNA 3′ end processing: reconstituting is believing
por: Yoon, Yoseop, et al.
Publicado: (2022)

Evidence for an Integrated Gene Repression Mechanism Based on mRNA Isoform Toggling in Human Cells
por: Hollerer, Ina, et al.
Publicado: (2019)

Automated High-Throughput RNAi Screening in Human Cells Combined with Reporter mRNA Transfection to Identify Novel Regulators of Translation
por: Casanova, Claudia M., et al.
Publicado: (2012)

Processing and transcriptome expansion at the mRNA 3′ end in health and disease: finding the right end
por: Ogorodnikov, Anton, et al.
Publicado: (2016)

Translation of poly(A) tails leads to precise mRNA cleavage
por: Guydosh, Nicholas R., et al.
Publicado: (2017)

Novel lentiviral vectors with mutated reverse transcriptase for mRNA delivery of TALE nucleases
por: Mock, Ulrike, et al.
Publicado: (2014)

Molecular mechanisms of eukaryotic pre-mRNA 3′ end processing regulation
por: Millevoi, Stefania, et al.
Publicado: (2010)

The export factor Yra1 modulates mRNA 3’ end processing
por: Johnson, Sara A., et al.
Publicado: (2011)

Dynamics in Fip1 regulate eukaryotic mRNA 3′ end processing
por: Kumar, Ananthanarayanan, et al.
Publicado: (2021)

Human histone pre-mRNA assembles histone or canonical mRNA-processing complexes by overlapping 3′-end sequence elements
por: Ielasi, Francesco S, et al.
Publicado: (2022)

Structure and Function of Pre-mRNA 5′-End Capping Quality Control and 3′-End Processing
por: Jurado, Ashley R., et al.
Publicado: (2014)

A tale of an A-tail: The lifeline of a SINE
por: Roy-Engel, Astrid M.
Publicado: (2012)

A Tale of Two Tails: Not Just Skin Deep
por: Dutta, Abhijit, et al.
Publicado: (2015)

Rapunzel Syndrome: Rare ‘Tale’ of a Broken ‘Tail’
por: Chauhan, Narvir S., et al.
Publicado: (2016)

A tale of two “tails:” A curiosity revisited
por: Sadashiva, Nishanth, et al.
Publicado: (2016)

Rapunzel Syndrome: A Concealed Tale of the Misleading Tail
por: Kumar, Deepak, et al.
Publicado: (2023)

Role of poly (A) tail as an identity element for mRNA nuclear export
por: Fuke, Hiroyuki, et al.
Publicado: (2008)

Molecular dissection of mRNA poly(A) tail length control in yeast
por: Viphakone, Nicolas, et al.
Publicado: (2008)

Birth of a poly(A) tail: mechanisms and control of mRNA polyadenylation
por: Rodríguez‐Molina, Juan B., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_537fplj4uq2b9m5mkhsg02ost0