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Pseudomonas aeruginosa elastase causes transient disruption of tight junctions and downregulation of PAR-2 in human nasal epithelial cells

BACKGROUND: Pseudomonas aeruginosa causes chronic respiratory disease, and the elastase enzyme that it produces increases the permeability of airway epithelial cells owing to the disruption of tight junctions. P. aeruginosa is also implicated in prolonged chronic rhinosinusitis. However, the effects...

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Detalles Bibliográficos
Autores principales:	Nomura, Kazuaki, Obata, Kazufumi, Keira, Takashi, Miyata, Ryo, Hirakawa, Satoshi, Takano, Ken-ichi, Kohno, Takayuki, Sawada, Norimasa, Himi, Tetsuo, Kojima, Takashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936699/ https://www.ncbi.nlm.nih.gov/pubmed/24548792 http://dx.doi.org/10.1186/1465-9921-15-21

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