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ARF induction in response to DNA strand breaks is regulated by PARP1

The ARF tumour suppressor protein, the gene of which is frequently mutated in many human cancers, plays an important role in the cellular stress response by orchestrating up-regulation of p53 protein and consequently promoting cell-cycle delay. Although p53 protein function has been clearly linked t...

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Detalles Bibliográficos
Autores principales:	Orlando, Giulia, Khoronenkova, Svetlana V., Dianova, Irina I., Parsons, Jason L., Dianov, Grigory L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936746/ https://www.ncbi.nlm.nih.gov/pubmed/24293653 http://dx.doi.org/10.1093/nar/gkt1185

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