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Adaptation of the Haloarcula hispanica CRISPR-Cas system to a purified virus strictly requires a priming process

The clustered regularly interspaced short palindromic repeat (CRISPR)-Cas system mediates adaptive immunity against foreign nucleic acids in prokaryotes. However, efficient adaptation of a native CRISPR to purified viruses has only been observed for the type II-A system from a Streptococcus thermoph...

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Detalles Bibliográficos
Autores principales: Li, Ming, Wang, Rui, Zhao, Dahe, Xiang, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936756/
https://www.ncbi.nlm.nih.gov/pubmed/24265226
http://dx.doi.org/10.1093/nar/gkt1154