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Mapping Hfq-RNA interaction surfaces using tryptophan fluorescence quenching
Hfq is a posttranscriptional riboregulator and RNA chaperone that binds small RNAs and target mRNAs to effect their annealing and message-specific regulation in response to environmental stressors. Structures of Hfq-RNA complexes indicate that U-rich sequences prefer the proximal face and A-rich seq...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936774/ https://www.ncbi.nlm.nih.gov/pubmed/24288369 http://dx.doi.org/10.1093/nar/gkt1171 |