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Increased peripheral and local soluble FGL2 in the recovery of renal ischemia reperfusion injury in a porcine kidney auto-transplantation model

BACKGROUND: Regulatory T cells (Treg) protect kidney against ischemia reperfusion (IR) injury via suppressing innate immunity, but the mechanism has not been fully clarified. Soluble fibrinogen-like protein 2 (sFGL2), a novel effector of Treg, may affect apoptosis and inflammation. This study invest...

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Detalles Bibliográficos
Autores principales: Zhao, Zitong, Yang, Cheng, Li, Long, Zhao, Tian, Wang, Lingyan, Rong, Ruiming, Yang, Bin, Xu, Ming, Zhu, Tongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936847/
https://www.ncbi.nlm.nih.gov/pubmed/24559374
http://dx.doi.org/10.1186/1479-5876-12-53