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Clinical characteristics and quality of life in women with COPD: an observational study
BACKGROUND: The impact of COPD on patient’s quality of life is well established, but gender differences have received little attention. METHODS: To describe factors associated with the health-related quality of life by gender: A cross-sectional observational study (NCT01007734) was conducted in COPD...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936943/ https://www.ncbi.nlm.nih.gov/pubmed/24555562 http://dx.doi.org/10.1186/1472-6874-14-31 |
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author | Raherison, Chantal Tillie-Leblond, Isabelle Prudhomme, Anne Taillé, Camille Biron, Elisabeth Nocent-Ejnaini, Cecilia Mathieu, Benigne Ostinelli, Juliette |
author_facet | Raherison, Chantal Tillie-Leblond, Isabelle Prudhomme, Anne Taillé, Camille Biron, Elisabeth Nocent-Ejnaini, Cecilia Mathieu, Benigne Ostinelli, Juliette |
author_sort | Raherison, Chantal |
collection | PubMed |
description | BACKGROUND: The impact of COPD on patient’s quality of life is well established, but gender differences have received little attention. METHODS: To describe factors associated with the health-related quality of life by gender: A cross-sectional observational study (NCT01007734) was conducted in COPD patients followed by pulmonologists. The first patient included had to be a woman. Data concerning the patient, COPD and their management were collected by the physician. The patient had to fill in several questionnaires: Saint-George Hospital respiratory Questionnaire (SGRQ-C), and motivation to quit smoking. RESULTS: Four hundred and thirty patients were included: mean age 63.9 ± 11.3 years; 57.4% were women. Women were significantly younger than men (61.9 vs. 66.6) and their tobacco use was lower (37.1 vs. 40.4 PY). Cardiovascular comorbidities were more frequent in men while osteoporosis, anxiety and depression were frequent in women. The frequency of cough, sputum and the severity of dyspnea did not differ significantly between genders. Lung function impairment was less severe in women than in men (mean FEV1 52% predicted normal vs. 47. 8%). Anxiety score was higher (score 9.8 vs. 7.1) and quality of life (SGRQ-C) more impaired in women (scores 50.6 vs. 45.4; p < 0.02) than in men. Moreover, in multivariate analysis, chronic sputum was associated with higher SGRQ-C scores in women but not in men. CONCLUSIONS: This study underlines that despite less airflow limitation, quality of life is more impacted by chronic sputum in women than in men. |
format | Online Article Text |
id | pubmed-3936943 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-39369432014-02-28 Clinical characteristics and quality of life in women with COPD: an observational study Raherison, Chantal Tillie-Leblond, Isabelle Prudhomme, Anne Taillé, Camille Biron, Elisabeth Nocent-Ejnaini, Cecilia Mathieu, Benigne Ostinelli, Juliette BMC Womens Health Research Article BACKGROUND: The impact of COPD on patient’s quality of life is well established, but gender differences have received little attention. METHODS: To describe factors associated with the health-related quality of life by gender: A cross-sectional observational study (NCT01007734) was conducted in COPD patients followed by pulmonologists. The first patient included had to be a woman. Data concerning the patient, COPD and their management were collected by the physician. The patient had to fill in several questionnaires: Saint-George Hospital respiratory Questionnaire (SGRQ-C), and motivation to quit smoking. RESULTS: Four hundred and thirty patients were included: mean age 63.9 ± 11.3 years; 57.4% were women. Women were significantly younger than men (61.9 vs. 66.6) and their tobacco use was lower (37.1 vs. 40.4 PY). Cardiovascular comorbidities were more frequent in men while osteoporosis, anxiety and depression were frequent in women. The frequency of cough, sputum and the severity of dyspnea did not differ significantly between genders. Lung function impairment was less severe in women than in men (mean FEV1 52% predicted normal vs. 47. 8%). Anxiety score was higher (score 9.8 vs. 7.1) and quality of life (SGRQ-C) more impaired in women (scores 50.6 vs. 45.4; p < 0.02) than in men. Moreover, in multivariate analysis, chronic sputum was associated with higher SGRQ-C scores in women but not in men. CONCLUSIONS: This study underlines that despite less airflow limitation, quality of life is more impacted by chronic sputum in women than in men. BioMed Central 2014-02-20 /pmc/articles/PMC3936943/ /pubmed/24555562 http://dx.doi.org/10.1186/1472-6874-14-31 Text en Copyright © 2014 Raherison et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. |
spellingShingle | Research Article Raherison, Chantal Tillie-Leblond, Isabelle Prudhomme, Anne Taillé, Camille Biron, Elisabeth Nocent-Ejnaini, Cecilia Mathieu, Benigne Ostinelli, Juliette Clinical characteristics and quality of life in women with COPD: an observational study |
title | Clinical characteristics and quality of life in women with COPD: an observational study |
title_full | Clinical characteristics and quality of life in women with COPD: an observational study |
title_fullStr | Clinical characteristics and quality of life in women with COPD: an observational study |
title_full_unstemmed | Clinical characteristics and quality of life in women with COPD: an observational study |
title_short | Clinical characteristics and quality of life in women with COPD: an observational study |
title_sort | clinical characteristics and quality of life in women with copd: an observational study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936943/ https://www.ncbi.nlm.nih.gov/pubmed/24555562 http://dx.doi.org/10.1186/1472-6874-14-31 |
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