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Clinical characteristics and quality of life in women with COPD: an observational study

BACKGROUND: The impact of COPD on patient’s quality of life is well established, but gender differences have received little attention. METHODS: To describe factors associated with the health-related quality of life by gender: A cross-sectional observational study (NCT01007734) was conducted in COPD...

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Autores principales: Raherison, Chantal, Tillie-Leblond, Isabelle, Prudhomme, Anne, Taillé, Camille, Biron, Elisabeth, Nocent-Ejnaini, Cecilia, Mathieu, Benigne, Ostinelli, Juliette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936943/
https://www.ncbi.nlm.nih.gov/pubmed/24555562
http://dx.doi.org/10.1186/1472-6874-14-31
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author Raherison, Chantal
Tillie-Leblond, Isabelle
Prudhomme, Anne
Taillé, Camille
Biron, Elisabeth
Nocent-Ejnaini, Cecilia
Mathieu, Benigne
Ostinelli, Juliette
author_facet Raherison, Chantal
Tillie-Leblond, Isabelle
Prudhomme, Anne
Taillé, Camille
Biron, Elisabeth
Nocent-Ejnaini, Cecilia
Mathieu, Benigne
Ostinelli, Juliette
author_sort Raherison, Chantal
collection PubMed
description BACKGROUND: The impact of COPD on patient’s quality of life is well established, but gender differences have received little attention. METHODS: To describe factors associated with the health-related quality of life by gender: A cross-sectional observational study (NCT01007734) was conducted in COPD patients followed by pulmonologists. The first patient included had to be a woman. Data concerning the patient, COPD and their management were collected by the physician. The patient had to fill in several questionnaires: Saint-George Hospital respiratory Questionnaire (SGRQ-C), and motivation to quit smoking. RESULTS: Four hundred and thirty patients were included: mean age 63.9 ± 11.3 years; 57.4% were women. Women were significantly younger than men (61.9 vs. 66.6) and their tobacco use was lower (37.1 vs. 40.4 PY). Cardiovascular comorbidities were more frequent in men while osteoporosis, anxiety and depression were frequent in women. The frequency of cough, sputum and the severity of dyspnea did not differ significantly between genders. Lung function impairment was less severe in women than in men (mean FEV1 52% predicted normal vs. 47. 8%). Anxiety score was higher (score 9.8 vs. 7.1) and quality of life (SGRQ-C) more impaired in women (scores 50.6 vs. 45.4; p < 0.02) than in men. Moreover, in multivariate analysis, chronic sputum was associated with higher SGRQ-C scores in women but not in men. CONCLUSIONS: This study underlines that despite less airflow limitation, quality of life is more impacted by chronic sputum in women than in men.
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spelling pubmed-39369432014-02-28 Clinical characteristics and quality of life in women with COPD: an observational study Raherison, Chantal Tillie-Leblond, Isabelle Prudhomme, Anne Taillé, Camille Biron, Elisabeth Nocent-Ejnaini, Cecilia Mathieu, Benigne Ostinelli, Juliette BMC Womens Health Research Article BACKGROUND: The impact of COPD on patient’s quality of life is well established, but gender differences have received little attention. METHODS: To describe factors associated with the health-related quality of life by gender: A cross-sectional observational study (NCT01007734) was conducted in COPD patients followed by pulmonologists. The first patient included had to be a woman. Data concerning the patient, COPD and their management were collected by the physician. The patient had to fill in several questionnaires: Saint-George Hospital respiratory Questionnaire (SGRQ-C), and motivation to quit smoking. RESULTS: Four hundred and thirty patients were included: mean age 63.9 ± 11.3 years; 57.4% were women. Women were significantly younger than men (61.9 vs. 66.6) and their tobacco use was lower (37.1 vs. 40.4 PY). Cardiovascular comorbidities were more frequent in men while osteoporosis, anxiety and depression were frequent in women. The frequency of cough, sputum and the severity of dyspnea did not differ significantly between genders. Lung function impairment was less severe in women than in men (mean FEV1 52% predicted normal vs. 47. 8%). Anxiety score was higher (score 9.8 vs. 7.1) and quality of life (SGRQ-C) more impaired in women (scores 50.6 vs. 45.4; p < 0.02) than in men. Moreover, in multivariate analysis, chronic sputum was associated with higher SGRQ-C scores in women but not in men. CONCLUSIONS: This study underlines that despite less airflow limitation, quality of life is more impacted by chronic sputum in women than in men. BioMed Central 2014-02-20 /pmc/articles/PMC3936943/ /pubmed/24555562 http://dx.doi.org/10.1186/1472-6874-14-31 Text en Copyright © 2014 Raherison et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.
spellingShingle Research Article
Raherison, Chantal
Tillie-Leblond, Isabelle
Prudhomme, Anne
Taillé, Camille
Biron, Elisabeth
Nocent-Ejnaini, Cecilia
Mathieu, Benigne
Ostinelli, Juliette
Clinical characteristics and quality of life in women with COPD: an observational study
title Clinical characteristics and quality of life in women with COPD: an observational study
title_full Clinical characteristics and quality of life in women with COPD: an observational study
title_fullStr Clinical characteristics and quality of life in women with COPD: an observational study
title_full_unstemmed Clinical characteristics and quality of life in women with COPD: an observational study
title_short Clinical characteristics and quality of life in women with COPD: an observational study
title_sort clinical characteristics and quality of life in women with copd: an observational study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936943/
https://www.ncbi.nlm.nih.gov/pubmed/24555562
http://dx.doi.org/10.1186/1472-6874-14-31
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