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LDsplit: screening for cis-regulatory motifs stimulating meiotic recombination hotspots by analysis of DNA sequence polymorphisms
BACKGROUND: As a fundamental genomic element, meiotic recombination hotspot plays important roles in life sciences. Thus uncovering its regulatory mechanisms has broad impact on biomedical research. Despite the recent identification of the zinc finger protein PRDM9 and its 13-mer binding motif as ma...
Autores principales: | Yang, Peng, Wu, Min, Guo, Jing, Kwoh, Chee Keong, Przytycka, Teresa M, Zheng, Jie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936957/ https://www.ncbi.nlm.nih.gov/pubmed/24533858 http://dx.doi.org/10.1186/1471-2105-15-48 |
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