G(i)α proteins exhibit functional differences in the activation of ERK1/2, Akt and mTORC1 by growth factors in normal and breast cancer cells

BACKGROUND: In a classic model, G(i)α proteins including G(i1)α, G(i2)α and G(i3)α are important for transducing signals from G(i)α protein-coupled receptors (G(i)αPCRs) to their downstream cascades in response to hormones and neurotransmitters. Our previous study has suggested that G(i1)α, G(i2)α a...

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Detalles Bibliográficos
Autores principales: Wang, Zhanwei, Dela Cruz, Rica, Ji, Fang, Guo, Sheng, Zhang, Jianhua, Wang, Ying, Feng, Gen-Sheng, Birnbaumer, Lutz, Jiang, Meisheng, Chu, Wen-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937014/
https://www.ncbi.nlm.nih.gov/pubmed/24521094
http://dx.doi.org/10.1186/1478-811X-12-10

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