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PAX5 fusion genes in t(7;9)(q11.2;p13) leukemia: a case report and review of the literature
BACKGROUND: B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is characterized by recurrent genetic alterations including chromosomal translocations. The transcription factor PAX5, which is pivotal for B-cell commitment and maintenance, is affected by rearrangements, which lead to the expressi...
Autores principales: | Denk, Dagmar, Bradtke, Jutta, König, Margit, Strehl, Sabine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937052/ https://www.ncbi.nlm.nih.gov/pubmed/24507461 http://dx.doi.org/10.1186/1755-8166-7-13 |
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