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Caught in the middle with multiple displacement amplification: the myth of pooling for avoiding multiple displacement amplification bias in a metagenome

BACKGROUND: Shotgun metagenomics has become an important tool for investigating the ecology of microorganisms. Underlying these investigations is the assumption that metagenome sequence data accurately estimates the census of microbial populations. Multiple displacement amplification (MDA) of microb...

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Detalles Bibliográficos
Autores principales:	Marine, Rachel, McCarren, Coleen, Vorrasane, Vansay, Nasko, Dan, Crowgey, Erin, Polson, Shawn W, Wommack, K Eric
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937105/ https://www.ncbi.nlm.nih.gov/pubmed/24475755 http://dx.doi.org/10.1186/2049-2618-2-3

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