IL-1β-induced activation of p38 promotes metastasis in gastric adenocarcinoma via upregulation of AP-1/c-fos, MMP2 and MMP9

BACKGROUND: Interleukin-1β (IL-1β) has been implicated in the progression of gastric adenocarcinoma (GA); however, the molecular mechanisms of action of IL-1β in GA are poorly characterized. P38 and JNK are the major MAPK family members that regulate IL-1β signaling pathways. Here, we investigated t...

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Detalles Bibliográficos
Autores principales: Huang, Qiaojia, Lan, Fenghua, Wang, Xiaoting, Yu, Yinghao, Ouyang, Xuenong, Zheng, Feng, Han, Junyong, Lin, Youdong, Xie, Yanchuan, Xie, Feilai, Liu, Wei, Yang, Xiaoli, Wang, Han, Dong, Lihong, Wang, Lie, Tan, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937117/
https://www.ncbi.nlm.nih.gov/pubmed/24479681
http://dx.doi.org/10.1186/1476-4598-13-18

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