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β-alanine suppresses malignant breast epithelial cell aggressiveness through alterations in metabolism and cellular acidity in vitro
BACKGROUND: Deregulated energetics is a property of most cancer cells. This phenomenon, known as the Warburg Effect or aerobic glycolysis, is characterized by increased glucose uptake, lactate export and extracellular acidification, even in the presence of oxygen. β-alanine is a non-essential amino...
Autores principales: | Vaughan, Roger A, Gannon, Nicholas P, Garcia-Smith, Randi, Licon-Munoz, Yamhilette, Barberena, Miguel A, Bisoffi, Marco, Trujillo, Kristina A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937146/ https://www.ncbi.nlm.nih.gov/pubmed/24460609 http://dx.doi.org/10.1186/1476-4598-13-14 |
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