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A Variant in the Neuropeptide Receptor npr-1 is a Major Determinant of Caenorhabditis elegans Growth and Physiology

The mechanistic basis for how genetic variants cause differences in phenotypic traits is often elusive. We identified a quantitative trait locus in Caenorhabditis elegans that affects three seemingly unrelated phenotypic traits: lifetime fecundity, adult body size, and susceptibility to the human pa...

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Detalles Bibliográficos
Autores principales: Andersen, Erik C., Bloom, Joshua S., Gerke, Justin P., Kruglyak, Leonid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937155/
https://www.ncbi.nlm.nih.gov/pubmed/24586193
http://dx.doi.org/10.1371/journal.pgen.1004156