Effect of omega-3 supplementation versus placebo on acylation stimulating protein receptor gene expression in type 2 diabetics

BACKGROUND: This randomized controlled trial investigated the role of omega-3 supplementation on C5L2 gene expression in type 2 diabetics. METHODS: Subjects in the omega-3 group received 4 g omega-3 per day and subjects in the placebo group took four capsules of placebo per day for 10 weeks. Gene ex...

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Detalles Bibliográficos
Autores principales: Farahbakhsh-Farsi, Payam, Djalali, Mahmoud, Koohdani, Fariba, Saboor-Yaraghi, Ali Akbar, Eshraghian, Mohammad Reza, Javanbakht, Mohammad Hassan, Chamari, Maryam, Djazayery, Abolghassem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937173/
https://www.ncbi.nlm.nih.gov/pubmed/24393631
http://dx.doi.org/10.1186/2251-6581-13-1
Descripción
Sumario:BACKGROUND: This randomized controlled trial investigated the role of omega-3 supplementation on C5L2 gene expression in type 2 diabetics. METHODS: Subjects in the omega-3 group received 4 g omega-3 per day and subjects in the placebo group took four capsules of placebo per day for 10 weeks. Gene expression was measured by RT- PCR at the beginning and end of the study. RESULTS: The results of this study show depletion in the omega-3 group, but the mean difference between two groups was not significant. CONCLUSIONS: Understanding the effect of the omega-3 pathway could contribute to targeting treatment of diabetes and its comorbidities.

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