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Serine Carboxypeptidase SCPEP1 and Cathepsin A Play Complementary Roles in Regulation of Vasoconstriction via Inactivation of Endothelin-1

The potent vasoconstrictor peptides, endothelin 1 (ET-1) and angiotensin II control adaptation of blood vessels to fluctuations of blood pressure. Previously we have shown that the circulating level of ET-1 is regulated through its proteolytic cleavage by secreted serine carboxypeptidase, cathepsin...

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Detalles Bibliográficos
Autores principales:	Pan, Xuefang, Grigoryeva, Lubov, Seyrantepe, Volkan, Peng, Junzheng, Kollmann, Katrin, Tremblay, Johanne, Lavoie, Julie L., Hinek, Aleksander, Lübke, Torben, Pshezhetsky, Alexey V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937211/ https://www.ncbi.nlm.nih.gov/pubmed/24586188 http://dx.doi.org/10.1371/journal.pgen.1004146

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