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Chk2 and P53 Regulate the Transmission of Healed Chromosomes in the Drosophila Male Germline

When a dicentric chromosome breaks in mitosis, the broken ends cannot be repaired by normal mechanisms that join two broken ends since each end is in a separate daughter cell. However, in the male germline of Drosophila melanogaster, a broken end may be healed by de novo telomere addition. We find t...

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Detalles Bibliográficos
Autores principales:	Titen, Simon W. A., Lin, Ho-Chen, Bhandari, Jayaram, Golic, Kent G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937212/ https://www.ncbi.nlm.nih.gov/pubmed/24586185 http://dx.doi.org/10.1371/journal.pgen.1004130

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