Cargando…

miR-100 Induces Epithelial-Mesenchymal Transition but Suppresses Tumorigenesis, Migration and Invasion

Whether epithelial-mesenchymal transition (EMT) is always linked to increased tumorigenicity is controversial. Through microRNA (miRNA) expression profiling of mammary epithelial cells overexpressing Twist, Snail or ZEB1, we identified miR-100 as a novel EMT inducer. Surprisingly, miR-100 inhibits t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Dahu, Sun, Yutong, Yuan, Yuan, Han, Zhenbo, Zhang, Peijing, Zhang, Jinsong, You, M. James, Teruya-Feldstein, Julie, Wang, Min, Gupta, Sumeet, Hung, Mien-Chie, Liang, Han, Ma, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937226/ https://www.ncbi.nlm.nih.gov/pubmed/24586203 http://dx.doi.org/10.1371/journal.pgen.1004177

Ejemplares similares

Deubiquitination and stabilization of PTEN by USP13
por: Zhang, Jinsong, et al.
Publicado: (2013)

ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1
por: Zhang, Peijing, et al.
Publicado: (2014)

Cyanidin-3-O-glucoside inhibits epithelial-to-mesenchymal transition, and migration and invasion of breast cancer cells by upregulating KLF4
por: Chen, Dahu, et al.
Publicado: (2020)

LincK contributes to breast tumorigenesis by promoting proliferation and epithelial-to-mesenchymal transition
por: Li, Jing, et al.
Publicado: (2019)

Molecular regulation of epithelial-to-mesenchymal transition in tumorigenesis (Review)
por: Škovierová, Henrieta, et al.
Publicado: (2018)

Sciellin mediates mesenchymal-to-epithelial transition in colorectal cancer hepatic metastasis
por: Chou, Chuan-Kai, et al.
Publicado: (2016)

Epigenetics, TET proteins, and hypoxia in epithelial-mesenchymal transition and tumorigenesis
por: Chen, Hsiao-Fan, et al.
Publicado: (2016)

Histone demethylase PHF8 promotes epithelial to mesenchymal transition and breast tumorigenesis
por: Shao, Peng, et al.
Publicado: (2017)

S100A9 promotes the proliferation and migration of cervical cancer cells by inducing epithelial-mesenchymal transition and activating the Wnt/β-catenin pathway
por: Zha, He, et al.
Publicado: (2019)

Cytoplasmic SIRT1 inhibits cell migration and invasion by impeding epithelial–mesenchymal transition in ovarian carcinoma
por: Yang, Tong, et al.
Publicado: (2019)

S100A7 promotes the migration, invasion and metastasis of human cervical cancer cells through epithelial–mesenchymal transition
por: Tian, Tian, et al.
Publicado: (2017)

Role of Bmi-1 in Regulation of Ionizing Irradiation-Induced Epithelial-Mesenchymal Transition and Migration of Breast Cancer Cells
por: Yuan, Weiwei, et al.
Publicado: (2015)

LincRNA-ROR induces epithelial-to-mesenchymal transition and contributes to breast cancer tumorigenesis and metastasis
por: Hou, P, et al.
Publicado: (2014)

Overexpression of NREP Promotes Migration and Invasion in Gastric Cancer Through Facilitating Epithelial-Mesenchymal Transition
por: Liu, Yuan-jie, et al.
Publicado: (2021)

The Effect of GPX2 on the Prognosis of Lung Adenocarcinoma Diagnosis and Proliferation, Migration, and Epithelial Mesenchymal Transition
por: Li, Yu-peng, et al.
Publicado: (2022)

Long Noncoding RNA LINC00909 Induces Epithelial-Mesenchymal Transition and Contributes to Osteosarcoma Tumorigenesis and Metastasis
por: Liu, Wanshun, et al.
Publicado: (2022)

ZDHHC11B is decreased in lung adenocarcinoma and inhibits tumorigenesis via regulating epithelial–mesenchymal transition
por: Dai, Huanyu, et al.
Publicado: (2023)

Collective and Individual Migration following the Epithelial-Mesenchymal Transition
por: Wong, Ian Y., et al.
Publicado: (2014)

FAM134B induces tumorigenesis and epithelial‐to‐mesenchymal transition via Akt signaling in hepatocellular carcinoma
por: Zhang, Zhao‐qi, et al.
Publicado: (2019)

Role of epithelial to mesenchymal transition associated genes in mammary gland regeneration and breast tumorigenesis
por: Sikandar, Shaheen S., et al.
Publicado: (2017)

Epithelial-Mesenchymal Transition in tumor microenvironment
por: Jing, Yingying, et al.
Publicado: (2011)

Intermediate cell states in epithelial-to-mesenchymal transition
por: Sha, Yutong, et al.
Publicado: (2019)

GOLPH3 induces epithelial–mesenchymal transition via Wnt/β‐catenin signaling pathway in epithelial ovarian cancer
por: Sun, Jing, et al.
Publicado: (2017)

Downregulation of KIAA1199 alleviated the activation, proliferation, and migration of hepatic stellate cells by the inhibition of epithelial–mesenchymal transition
por: Liu, Jingmei, et al.
Publicado: (2023)

Role of LncRNAs in the Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma
por: Ge, Xiaoyong, et al.
Publicado: (2021)

MicroRNA-21 stimulates epithelial-to-mesenchymal transition and tumorigenesis in clear cell renal cells
por: CAO, JIAN, et al.
Publicado: (2016)

lncRNA SNHG7 promotes tumorigenesis of nasopharyngeal carcinoma via epithelial-to-mesenchymal transition
por: Xu, Wenrui, et al.
Publicado: (2020)

lncRNA SNHG7 promotes tumorigenesis of nasopharyngeal carcinoma via epithelial-to-mesenchymal transition
por: Xu, Wenrui, et al.
Publicado: (2020)

ESR2 Drives Mesenchymal-to-Epithelial Transition in Triple-Negative Breast Cancer and Tumorigenesis In Vivo
por: Piperigkou, Zoi, et al.
Publicado: (2022)

Epithelial-to-Mesenchymal Transition Supports Ovarian Carcinosarcoma Tumorigenesis and Confers Sensitivity to Microtubule Targeting with Eribulin
por: Ho, Gwo Yaw, et al.
Publicado: (2022)

Active legumain promotes invasion and migration of neuroblastoma by regulating epithelial-mesenchymal transition
por: Zhang, Min, et al.
Publicado: (2022)

Cancer Targeted Gene Therapy of BikDD Inhibits Orthotopic Lung Cancer Growth and Improves Long-term Survival
por: Sher, Yuh-Pyng, et al.
Publicado: (2009)

ZNF488 Enhances the Invasion and Tumorigenesis in Nasopharyngeal Carcinoma Via the Wnt Signaling Pathway Involving Epithelial Mesenchymal Transition
por: Zong, Dan, et al.
Publicado: (2016)

S100A4 promotes colon inflammation and colitis-associated colon tumorigenesis
por: Zhang, Jinhua, et al.
Publicado: (2018)

Polarity and epithelial-mesenchymal transition of retinal pigment epithelial cells in proliferative vitreoretinopathy
por: Zou, Hui, et al.
Publicado: (2020)

The miR-370/UQCRC2 axis facilitates tumorigenesis by regulating epithelial-mesenchymal transition in Gastric Cancer
por: Wang, Dan-wen, et al.
Publicado: (2020)

The role of DYNLT3 in breast cancer proliferation, migration, and invasion via epithelial‐to‐mesenchymal transition
por: Wang, Han, et al.
Publicado: (2023)

WTX inhibits gastric cancer migration through the reversal of epithelial-mesenchymal transition
por: Ye, Danli, et al.
Publicado: (2018)

MTBP promotes migration and invasion by regulation of ZEB2-mediated epithelial–mesenchymal transition in lung cancer cells
por: Pan, Bo, et al.
Publicado: (2018)

Intracellular and extracellular S100A9 trigger epithelial-mesenchymal transition and promote the invasive phenotype of pituitary adenoma through activation of AKT1
por: Huang, Ning, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_8vrp6jf6gu4nipq1qse5d4rudu