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MicroRNAs Located in the Hox Gene Clusters Are Implicated in Huntington's Disease Pathogenesis

Transcriptional dysregulation has long been recognized as central to the pathogenesis of Huntington's disease (HD). MicroRNAs (miRNAs) represent a major system of post-transcriptional regulation, by either preventing translational initiation or by targeting transcripts for storage or for degrad...

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Detalles Bibliográficos
Autores principales:	Hoss, Andrew G., Kartha, Vinay K., Dong, Xianjun, Latourelle, Jeanne C., Dumitriu, Alexandra, Hadzi, Tiffany C., MacDonald, Marcy E., Gusella, James F., Akbarian, Schahram, Chen, Jiang-Fan, Weng, Zhiping, Myers, Richard H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937267/ https://www.ncbi.nlm.nih.gov/pubmed/24586208 http://dx.doi.org/10.1371/journal.pgen.1004188

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