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Structure of the Membrane Anchor of Pestivirus Glycoprotein E(rns), a Long Tilted Amphipathic Helix
E(rns) is an essential virion glycoprotein with RNase activity that suppresses host cellular innate immune responses upon being partially secreted from the infected cells. Its unusual C-terminus plays multiple roles, as the amphiphilic helix acts as a membrane anchor, as a signal peptidase cleavage...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937272/ https://www.ncbi.nlm.nih.gov/pubmed/24586172 http://dx.doi.org/10.1371/journal.ppat.1003973 |