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Memantine, an Antagonist of the NMDA Glutamate Receptor, Affects Cell Proliferation, Differentiation and the Intracellular Cycle and Induces Apoptosis in Trypanosoma cruzi
Chagas' disease is caused by the protozoan parasite Trypanosoma cruzi and affects approximately 10 million people in endemic areas of Mexico and Central and South America. Currently available chemotherapies are limited to two compounds: Nifurtimox and Benznidazole. Both drugs reduce the symptom...
Autores principales: | Damasceno, Flávia Silva, Barisón, María Julia, Pral, Elisabeth Mieko Furusho, Paes, Lisvane Silva, Silber, Ariel Mariano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937314/ https://www.ncbi.nlm.nih.gov/pubmed/24587468 http://dx.doi.org/10.1371/journal.pntd.0002717 |
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