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Metabolic Reprogramming during Purine Stress in the Protozoan Pathogen Leishmania donovani

The ability of Leishmania to survive in their insect or mammalian host is dependent upon an ability to sense and adapt to changes in the microenvironment. However, little is known about the molecular mechanisms underlying the parasite response to environmental changes, such as nutrient availability....

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Detalles Bibliográficos
Autores principales: Martin, Jessica L., Yates, Phillip A., Soysa, Radika, Alfaro, Joshua F., Yang, Feng, Burnum-Johnson, Kristin E., Petyuk, Vladislav A., Weitz, Karl K., Camp, David G., Smith, Richard D., Wilmarth, Phillip A., David, Larry L., Ramasamy, Gowthaman, Myler, Peter J., Carter, Nicola S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937319/
https://www.ncbi.nlm.nih.gov/pubmed/24586154
http://dx.doi.org/10.1371/journal.ppat.1003938