Polar Localization of PhoN2, a Periplasmic Virulence-Associated Factor of Shigella flexneri, Is Required for Proper IcsA Exposition at the Old Bacterial Pole

Proper protein localization is critical for bacterial virulence. PhoN2 is a virulence-associated ATP-diphosphohydrolase (apyrase) involved in IcsA-mediated actin-based motility of S. flexneri. Herein, by analyzing a ΔphoN2 mutant of the S. flexneri strain M90T and by generating phoN2::HA fusions, we...

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Detalles Bibliográficos
Autores principales: Scribano, Daniela, Petrucca, Andrea, Pompili, Monica, Ambrosi, Cecilia, Bruni, Elena, Zagaglia, Carlo, Prosseda, Gianni, Nencioni, Lucia, Casalino, Mariassunta, Polticelli, Fabio, Nicoletti, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937361/
https://www.ncbi.nlm.nih.gov/pubmed/24587292
http://dx.doi.org/10.1371/journal.pone.0090230

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