Silencing of miR-34a Attenuates Cardiac Dysfunction in a Setting of Moderate, but Not Severe, Hypertrophic Cardiomyopathy

Therapeutic inhibition of the miR-34 family (miR-34a,-b,-c), or miR-34a alone, have emerged as promising strategies for the treatment of cardiac pathology. However, before advancing these approaches further for potential entry into the clinic, a more comprehensive assessment of the therapeutic poten...

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Detalles Bibliográficos
Autores principales: Bernardo, Bianca C., Gao, Xiao-Ming, Tham, Yow Keat, Kiriazis, Helen, Winbanks, Catherine E., Ooi, Jenny Y. Y., Boey, Esther J. H., Obad, Susanna, Kauppinen, Sakari, Gregorevic, Paul, Du, Xiao-Jun, Lin, Ruby C. Y., McMullen, Julie R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937392/
https://www.ncbi.nlm.nih.gov/pubmed/24587330
http://dx.doi.org/10.1371/journal.pone.0090337

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