Syncytiotrophoblast Vesicles Show Altered micro-RNA and Haemoglobin Content after Ex-vivo Perfusion of Placentas with Haemoglobin to Mimic Preeclampsia

BACKGROUND: Cell-free foetal haemoglobin (HbF) has been shown to play a role in the pathology of preeclampsia (PE). In the present study, we aimed to further characterize the harmful effects of extracellular free haemoglobin (Hb) on the placenta. In particular, we investigated whether cell-free Hb a...

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Detalles Bibliográficos
Autores principales: Cronqvist, Tina, Saljé, Karen, Familari, Mary, Guller, Seth, Schneider, Henning, Gardiner, Chris, Sargent, Ian L., Redman, Christopher W., Mörgelin, Matthias, Åkerström, Bo, Gram, Magnus, Hansson, Stefan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937405/
https://www.ncbi.nlm.nih.gov/pubmed/24587192
http://dx.doi.org/10.1371/journal.pone.0090020

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