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Therapeutic wounding - 88% phenol in idiopathic guttate hypomelanosis

CONTEXT: Therapeutic wounding includes wounding the skin to induce pigmentation of the depigmented skin patches that was earlier used for repigmenting small patches of stable vitiligo. In this study, we have used the same principle to induce pigmentation in idiopathic guttate hypomelanosis (IGH) by...

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Autores principales: Ravikiran, Shilpashree P., Sacchidanand, S., Leelavathy, B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937479/
https://www.ncbi.nlm.nih.gov/pubmed/24616848
http://dx.doi.org/10.4103/2229-5178.126021
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author Ravikiran, Shilpashree P.
Sacchidanand, S.
Leelavathy, B.
author_facet Ravikiran, Shilpashree P.
Sacchidanand, S.
Leelavathy, B.
author_sort Ravikiran, Shilpashree P.
collection PubMed
description CONTEXT: Therapeutic wounding includes wounding the skin to induce pigmentation of the depigmented skin patches that was earlier used for repigmenting small patches of stable vitiligo. In this study, we have used the same principle to induce pigmentation in idiopathic guttate hypomelanosis (IGH) by spot peel with 88% phenol. AIMS: To study the efficacy of phenol in causing repigmentation in IGH and its adverse effect profile. SETTINGS AND DESIGN: Open prospective study. MATERIALS AND METHODS: Twenty patients with 139 IGH macules were subjected to spot peel. Eighty-eight percent phenol was applied with an ear bud once a month for two sittings. Patients were assessed both subjectively and objectively after every session and at the end of 3 months of initiation of therapy. RESULTS: Repigmentation was noted in 64% of IGH macules. More than 75% improvement was seen in 45% of the total IGH macules, while 41.5% showed 50-75% improvement at the end of three months. Persistent scabbing was the common adverse effect noted in 17.26% of lesions. CONCLUSION: Spot peel with 88% phenol is a safe, simple, cost-effective, outpatient procedure for IGH, which can be combined with other medical therapies.
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spelling pubmed-39374792014-03-10 Therapeutic wounding - 88% phenol in idiopathic guttate hypomelanosis Ravikiran, Shilpashree P. Sacchidanand, S. Leelavathy, B. Indian Dermatol Online J Original Article CONTEXT: Therapeutic wounding includes wounding the skin to induce pigmentation of the depigmented skin patches that was earlier used for repigmenting small patches of stable vitiligo. In this study, we have used the same principle to induce pigmentation in idiopathic guttate hypomelanosis (IGH) by spot peel with 88% phenol. AIMS: To study the efficacy of phenol in causing repigmentation in IGH and its adverse effect profile. SETTINGS AND DESIGN: Open prospective study. MATERIALS AND METHODS: Twenty patients with 139 IGH macules were subjected to spot peel. Eighty-eight percent phenol was applied with an ear bud once a month for two sittings. Patients were assessed both subjectively and objectively after every session and at the end of 3 months of initiation of therapy. RESULTS: Repigmentation was noted in 64% of IGH macules. More than 75% improvement was seen in 45% of the total IGH macules, while 41.5% showed 50-75% improvement at the end of three months. Persistent scabbing was the common adverse effect noted in 17.26% of lesions. CONCLUSION: Spot peel with 88% phenol is a safe, simple, cost-effective, outpatient procedure for IGH, which can be combined with other medical therapies. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC3937479/ /pubmed/24616848 http://dx.doi.org/10.4103/2229-5178.126021 Text en Copyright: © Indian Dermatology Online Journal http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Ravikiran, Shilpashree P.
Sacchidanand, S.
Leelavathy, B.
Therapeutic wounding - 88% phenol in idiopathic guttate hypomelanosis
title Therapeutic wounding - 88% phenol in idiopathic guttate hypomelanosis
title_full Therapeutic wounding - 88% phenol in idiopathic guttate hypomelanosis
title_fullStr Therapeutic wounding - 88% phenol in idiopathic guttate hypomelanosis
title_full_unstemmed Therapeutic wounding - 88% phenol in idiopathic guttate hypomelanosis
title_short Therapeutic wounding - 88% phenol in idiopathic guttate hypomelanosis
title_sort therapeutic wounding - 88% phenol in idiopathic guttate hypomelanosis
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937479/
https://www.ncbi.nlm.nih.gov/pubmed/24616848
http://dx.doi.org/10.4103/2229-5178.126021
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