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Divergence in a master variator generates distinct phenotypes and transcriptional responses

Genetic basis of phenotypic differences in individuals is an important area in biology and personalized medicine. Analysis of divergent Saccharomyces cerevisiae strains grown under different conditions revealed extensive variation in response to both drugs (e.g., 4-nitroquinoline 1-oxide [4NQO]) and...

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Detalles Bibliográficos
Autores principales: Gallagher, Jennifer E.G., Zheng, Wei, Rong, Xiaoqing, Miranda, Noraliz, Lin, Zhixiang, Dunn, Barbara, Zhao, Hongyu, Snyder, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937518/
https://www.ncbi.nlm.nih.gov/pubmed/24532717
http://dx.doi.org/10.1101/gad.228940.113

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