Antisense Oligonucleotides Targeting Parasite Inositol 1,4,5-Trisphosphate Receptor Inhibits Mammalian Host Cell Invasion by Trypanosoma cruzi

Chagas disease is caused by an intracellular parasitic protist, Trypanosoma cruzi. As there are no highly effective drugs against this agent that also demonstrate low toxicity, there is an urgent need for development of new drugs to treat Chagas disease. We have previously demonstrated that the para...

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Detalles Bibliográficos
Autores principales: Hashimoto, Muneaki, Nara, Takeshi, Hirawake, Hiroko, Morales, Jorge, Enomoto, Masahiro, Mikoshiba, Katsuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937783/
https://www.ncbi.nlm.nih.gov/pubmed/24577136
http://dx.doi.org/10.1038/srep04231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937783/
https://www.ncbi.nlm.nih.gov/pubmed/24577136
http://dx.doi.org/10.1038/srep04231

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