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Counting and Correcting Thermodynamically Infeasible Flux Cycles in Genome-Scale Metabolic Networks
Thermodynamics constrains the flow of matter in a reaction network to occur through routes along which the Gibbs energy decreases, implying that viable steady-state flux patterns should be void of closed reaction cycles. Identifying and removing cycles in large reaction networks can unfortunately be...
Autores principales: | De Martino, Daniele, Capuani, Fabrizio, Mori, Matteo, De Martino, Andrea, Marinari, Enzo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International (MDPI)
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937828/ https://www.ncbi.nlm.nih.gov/pubmed/24958259 http://dx.doi.org/10.3390/metabo3040946 |
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