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Counting and Correcting Thermodynamically Infeasible Flux Cycles in Genome-Scale Metabolic Networks

Thermodynamics constrains the flow of matter in a reaction network to occur through routes along which the Gibbs energy decreases, implying that viable steady-state flux patterns should be void of closed reaction cycles. Identifying and removing cycles in large reaction networks can unfortunately be...

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Detalles Bibliográficos
Autores principales: De Martino, Daniele, Capuani, Fabrizio, Mori, Matteo, De Martino, Andrea, Marinari, Enzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937828/
https://www.ncbi.nlm.nih.gov/pubmed/24958259
http://dx.doi.org/10.3390/metabo3040946

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