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The prognostic role of intragenic copy number breakpoints and identification of novel fusion genes in paediatric high grade glioma

BACKGROUND: Paediatric high grade glioma (pHGG) is a distinct biological entity to histologically similar tumours arising in older adults, and has differing copy number profiles and driver genetic alterations. As functionally important intragenic copy number aberrations (iCNA) and fusion genes begin...

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Detalles Bibliográficos
Autores principales: Carvalho, Diana, Mackay, Alan, Bjerke, Lynn, Grundy, Richard G, Lopes, Celeste, Reis, Rui M, Jones, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938307/
https://www.ncbi.nlm.nih.gov/pubmed/24548782
http://dx.doi.org/10.1186/2051-5960-2-23