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CCR5 Conformations Are Dynamic and Modulated by Localization, Trafficking and G Protein Association

CCR5 acts as the principal coreceptor during HIV-1 transmission and early stages of infection. Efficient HIV-1 entry requires a series of processes, many dependent on the conformational state of both viral envelope protein and cellular receptor. Monoclonal antibodies (MAbs) are able to identify diff...

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Detalles Bibliográficos
Autores principales: Flegler, Ayanna J., Cianci, Gianguido C., Hope, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938464/
https://www.ncbi.nlm.nih.gov/pubmed/24586501
http://dx.doi.org/10.1371/journal.pone.0089056

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