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CCR5 Conformations Are Dynamic and Modulated by Localization, Trafficking and G Protein Association
CCR5 acts as the principal coreceptor during HIV-1 transmission and early stages of infection. Efficient HIV-1 entry requires a series of processes, many dependent on the conformational state of both viral envelope protein and cellular receptor. Monoclonal antibodies (MAbs) are able to identify diff...
Autores principales: | Flegler, Ayanna J., Cianci, Gianguido C., Hope, Thomas J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938464/ https://www.ncbi.nlm.nih.gov/pubmed/24586501 http://dx.doi.org/10.1371/journal.pone.0089056 |
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