RNF8-Independent Lys63 Poly-Ubiquitylation Prevents Genomic Instability in Response to Replication-Associated DNA Damage

The cellular response to DNA double strand breaks (DSBs) involves the ordered assembly of repair proteins at or near sites of damage. This process is mediated through post-translational protein modifications that include both phosphorylation and ubiquitylation. Recent data have demonstrated that rec...

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Detalles Bibliográficos
Autores principales: Ramaekers, Chantal H. M. A., van den Beucken, Twan, Bristow, Robert G., Chiu, Roland K., Durocher, Daniel, Wouters, Bradly G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938561/
https://www.ncbi.nlm.nih.gov/pubmed/24587176
http://dx.doi.org/10.1371/journal.pone.0089997

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938561/
https://www.ncbi.nlm.nih.gov/pubmed/24587176
http://dx.doi.org/10.1371/journal.pone.0089997

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