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RNF8-Independent Lys63 Poly-Ubiquitylation Prevents Genomic Instability in Response to Replication-Associated DNA Damage
The cellular response to DNA double strand breaks (DSBs) involves the ordered assembly of repair proteins at or near sites of damage. This process is mediated through post-translational protein modifications that include both phosphorylation and ubiquitylation. Recent data have demonstrated that rec...
Autores principales: | Ramaekers, Chantal H. M. A., van den Beucken, Twan, Bristow, Robert G., Chiu, Roland K., Durocher, Daniel, Wouters, Bradly G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938561/ https://www.ncbi.nlm.nih.gov/pubmed/24587176 http://dx.doi.org/10.1371/journal.pone.0089997 |
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