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Syntaxin 1B, but Not Syntaxin 1A, Is Necessary for the Regulation of Synaptic Vesicle Exocytosis and of the Readily Releasable Pool at Central Synapses
Two syntaxin 1 (STX1) isoforms, HPC-1/STX1A and STX1B, are coexpressed in neurons and function as neuronal target membrane (t)-SNAREs. However, little is known about their functional differences in synaptic transmission. STX1A null mutant mice develop normally and do not show abnormalities in fast s...
Autores principales: | Mishima, Tatsuya, Fujiwara, Tomonori, Sanada, Masumi, Kofuji, Takefumi, Kanai-Azuma, Masami, Akagawa, Kimio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938564/ https://www.ncbi.nlm.nih.gov/pubmed/24587181 http://dx.doi.org/10.1371/journal.pone.0090004 |
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