An evolutionary ratchet leading to loss of elongation factors in eukaryotes

BACKGROUND: The GTPase eEF1A is the eukaryotic factor responsible for the essential, universal function of aminoacyl-tRNA delivery to the ribosome. Surprisingly, eEF1A is not universally present in eukaryotes, being replaced by the paralog EFL independently in multiple lineages. The driving force be...

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Detalles Bibliográficos
Autores principales: Atkinson, Gemma C, Kuzmenko, Anton, Chicherin, Ivan, Soosaar, Axel, Tenson, Tanel, Carr, Martin, Kamenski, Piotr, Hauryliuk, Vasili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938643/
https://www.ncbi.nlm.nih.gov/pubmed/24564225
http://dx.doi.org/10.1186/1471-2148-14-35

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938643/
https://www.ncbi.nlm.nih.gov/pubmed/24564225
http://dx.doi.org/10.1186/1471-2148-14-35

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