Antibody-Mediated Inhibition of TNFR1 Attenuates Disease in a Mouse Model of Multiple Sclerosis

Tumour necrosis factor (TNF) is a proinflammatory cytokine that is known to regulate inflammation in a number of autoimmune diseases, including multiple sclerosis (MS). Although targeting of TNF in models of MS has been successful, the pathological role of TNF in MS remains unclear due to clinical t...

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Detalles Bibliográficos
Autores principales: Williams, Sarah K., Maier, Olaf, Fischer, Roman, Fairless, Richard, Hochmeister, Sonja, Stojic, Aleksandar, Pick, Lara, Haar, Doreen, Musiol, Sylvia, Storch, Maria K., Pfizenmaier, Klaus, Diem, Ricarda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938650/
https://www.ncbi.nlm.nih.gov/pubmed/24587232
http://dx.doi.org/10.1371/journal.pone.0090117

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