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Death Receptor (DR4) Haplotypes Are Associated with Increased Susceptibility of Gallbladder Carcinoma in North Indian Population

BACKGROUND AND AIM: Defective apoptosis is a hallmark of cancer development and progression. Death receptors (DR4, FAS) and their ligands (TRAIL, FASL) are thought to mediate the major extrinsic apoptotic pathway in the cell. SNPs in these genes may lead to defective apoptosis. Hence, the present st...

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Detalles Bibliográficos
Autores principales:	Rai, Rajani, Sharma, Kiran L., Sharma, Surbhi, Misra, Sanjeev, Kumar, Ashok, Mittal, Balraj
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938657/ https://www.ncbi.nlm.nih.gov/pubmed/24587306 http://dx.doi.org/10.1371/journal.pone.0090264

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